General Cell Based Assays
Eurofins Discoverx PathHunter eXpress GPR3 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0626E2CP1L)
The PathHunter GPR3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR3 and EA-tagged β-Arrestin-2. Activation of GPR3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam Soluble Epoxide Hydrolase Assay Kit
Soluble Epoxide Hydrolase Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Revvity Health Sciences Inc HTRF mAb Anti-GST Eu-Conjugate, 20,000 Assay Points
HTRF mAb Anti-GST Eu-Conjugate, 20,000 Assay Points
Revvity Health Sciences Inc HTRF cAMP Gs HiRange Detection Kit Standard
HTRF cAMP Gs HiRange Detection Kit Standard
Eurofins Discoverx PathHunter eXpress mCXCR4 U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0481E3MCP5L)
The PathHunter mCXCR4 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CXCL12/SDF-1α) based activation of mCXCR4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCXCR4 and EA-tagged β-Arrestin-2. Activation of mCXCR4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery RPLEX HUM Cathepsin L2 ASYQP
The R-PLEX Human Cathepsin L2 Assay is a multiplex immunoassay kit from Meso Scale Diagnostics that allows for the quantitative measurement of human Cathepsin L2 in serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity up to 5 logs of dynamic range and low sample volume requirements This assay kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with an ECL tag calibrators and diluents needed to perform the assay It can detect Cathepsin L2 concentrations as low as 3 2 pg/mL with an upper limit of 100 000 pg/mL
Meso Scale Discovery R-PLEX Human GFAP ASY
The R-PLEX Human GFAP Assay Kit from Meso Scale Discovery measures glial fibrillary acidic protein (GFAP) in human samples using electrochemiluminescence (ECL) technology It offers high sensitivity a wide dynamic range and low sample volume requirements The kit includes a 96-well plate with capture and detection antibodies Read Buffer Sample Diluent and calibrators for standard curve generation It quantifies GFAP a biomarker in astrocytes linked to CNS disorders with a 2 5-hour protocol for high-throughput profiling
Cell Biolabs Inc CytoSelect™ 24-Well Cell Migration and Invasion Assay Combo Kit (8 µm, Fluorometric), 2x12 assays
Chemotaxis, a type of cell migration, is a highly integrated, multistep process that orchestrates embryonic morphogenesis, tissue repair and regeneration. Cell invasion is the ability of malignant tumor cells to invade normal surrounding tissue, which contributes in large part to the significant morbidity and mortality of cancers. The CytoSelect™ Cell Migration and Invasion Assay Kit utilizes polycarbonate membrane inserts (8 µm pore size) to assay the invasive properties of cells. The kit contains twelve 8 um uncoated polycarbonate membrane inserts, and another twelve 8 um polycarbonate membrane inserts coated with an ECM gel layer in a 24-well plate. Cells must degrade the ECM layer and then move through the pores of the membrane. Invasive cells are then quantified using the provided fluorometric dye.
Eurofins Discoverx PathHunter Human FGR Kinase Activity Cell-Based Assay Kit (U2OS)
The PathHunter Human FGR Stable Cell Line Kinase Activity Assay (U2OS) measures FGR CTK activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Genscript Corporation ToxinSensor Single Tests Kit
GenScript ToxinSensor Single Tests Kit with Standard is designed to be a qualitative In Vitro end-point endotoxin test for human and animal parenteral drugs biological products and medical devices Tachypleus Amebocyte Lysate (TAL) as supplied is to be reconstituted with sample or control directly After incubation for 1 hour and in the presence of endotoxin gelation occurs in the absence of endotoxin gelation does not occur GenScript supply a series of ToxinSensorTM Single Tests Kits with Standard with different sensitivity (0 03 EU/ml 0 06 EU/ml 0 125 EU/ml and 0 25 EU/ml)
Innovative Research Inc Hmn uPA Rcmb LMW 1mg
Human Urokinase (uPA) Recombinant Low Molecular Weight 1mg - Human Urokinase (uPA) Recombinant Low Molecular Weight from Innovative Research has been recombinantly produced in insect cells and purified using a combination of conventional and affinity chromatography. This is a frozen liquid buffered in 0.05M Sodium Acetate; 0.1M NaCl; 1mM EDTA; pH 5.0 and a purity of 95%. It is useful as a positive control for ELISA and western blot and and other applications including cell differentiation, cell signaling, clotting assays, fibrinolysis, plasminogen activation, protein-protein interactions, receptor binding, thromboelastography, and thrombolysis. Purified from auto-catalytic digestion of recombinant human urokinase produced in insect cells. Active two-chain low molecular weight human urokinase contains the proteinase domain and is separated from the amino terminal fragment by cleavage at the Lys135-Lys136 bond.
Eurofins Discoverx PathHunter eXpress GPR15 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0682E2CP1M)
The PathHunter GPR15 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR15 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR15 and EA-tagged β-Arrestin-2. Activation of GPR15 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
ABclonal Technology LDH-B
This gene encodes the B subunit of lactate dehydrogenase enzyme which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD in a post-glycolysis process Alternatively spliced transcript variants have been found for this gene Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism and that this isoform is localized in the peroxisomes Mutations in this gene are associated with lactate dehydrogenase B deficiency Pseudogenes have been identified on chromosomes X 5 and 13
Abcam Glycogen Assay Kit II (Colorimetric)
Glycogen Assay Kit II (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement